Table 2.
Comparison between Jagged1 gene methylation and patient clinicopathological parameters
| Parameters | N | Jagged1 (Mean methylation %) | |||
|---|---|---|---|---|---|
|
| |||||
| Overall | CpG_8.9.10 | CpG_11.12 | CpG_23.24.25 | ||
| Lymph node metastasis | |||||
| - (LNN) | 39 | 13.15* | 9.92* | 11.72 | 11.64 |
| + (LNP) | 34 | 10.81 | 5.70 | 9.03 | 9.30 |
| TNM stage | |||||
| I | 10 | 15.19* | 12.1* | 12.50 | 13.8* |
| II | 29 | 12.47 | 9.26 | 11.62 | 10.85 |
| III | 34 | 10.42 | 4.96 | 8.41 | 9.07 |
| Histological grade | |||||
| 1 | 8 | 16.02* | 9.00 | 19.88* | 15.38 |
| 2 | 57 | 12.03 | 7.77 | 10.75 | 10.71 |
| 3 | 8 | 9.58 | 7.25 | 6.38 | 10.50 |
| Receptor status | |||||
| ER(+)/PR(+) Her2(-) | 52 | 12.63 | 6.40 | 10.80 | 10.20 |
| ER(-) PR(-) Her2(+) | 12 | 11.44 | 5.28 | 8.28 | 9.65 |
ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2.
*
P<0.001.