Table 4.
Association of methyaltion with expression of Jagged1 and Notch1 genes in BC
| Jagged1 expression | Jagged1 (Mean methylation %) | Notch1 expression | Notch1 (Mean methylation %) | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||||||||||||
| N | Overall | CpG_1 | CpG_3.4.5 | CpG_8.9.10 | CpG_11.12 | CpG_14.15 | N | Overall | CpG_3 | CpG_4.5 | CpG_8 | CpG_9 | CpG_12.13 | CpG_14.15.16 | CpG_17 | CpG_19 | CpG_20 | ||
| High | 42 | 10.71* | 6.12* | 19.61* | 6.36* | 7.50* | 10.32* | High | 52 | 11.54* | 13.81* | 16.39* | 11.40* | 6.95* | 13.39* | 7.93* | 11.59* | 12.56* | 19.56* |
| Low | 31 | 13.06 | 11.36 | 24.35 | 9.36 | 10.92 | 13.97 | Low | 21 | 20.42 | 29.93 | 31.31 | 25.77 | 18 | 24.21 | 15.07 | 22.86 | 18.29 | 23.23 |
*
P<0.05.