Table 5.
Association of expression of Jagged1 and Notch1 with clinicopathological variables
| Parameters | N | Jagged1 expression | Notch1 expression | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
| High n (%) | Low n (%) | χ2 | P | High n (%) | Low n (%) | χ2 | P | ||
| Lymph node metastasis | |||||||||
| - (LNN) | 39 | 22 (56.4%) | 17 (43.6%) | 5.665 | 0.023* | 24 (61.5%) | 15 (38.5%) | 5.153 | 0.023* |
| + (LNP) | 34 | 28 (82.4%) | 6 (17.6%) | 29 (85.3%) | 5 (14.7%) | ||||
| TNM stage | |||||||||
| I | 10 | 3 (30.0%) | 7 (70.0%) | 6.475 | 0.041* | 7 (70.0%) | 3 (30.0%) | 6.772 | 0.034* |
| II | 29 | 16 (55.2%) | 13 (44.8%) | 15 (51.7%) | 14 (48.3%) | ||||
| III | 34 | 25 (73.5%) | 9 (26.5%) | 28 (82.4%) | 6 (17.6%) | ||||
| Histological grade | |||||||||
| 1 | 8 | 3 (37.5%) | 5 (62.5%) | 7.107 | 0.021* | 3 (37.5%) | 5 (62.5%) | 6.783 | 0.040* |
| 2 | 57 | 15 (26.3%) | 42 (73.7%) | 22 (38.6%) | 35 (61.4%) | ||||
| 3 | 8 | 6 (75.0%) | 2 (25.0%) | 7 (87.5%) | 1 (12.5%) | ||||
| Receptor status | |||||||||
| ER(+)/PR(+) Her2(-) | 52 | 37 (71.2%) | 15 (28.8%) | 0.071 | 0.789 | 26 (50.0%) | 26 (50.0%) | 4.402 | 0.036* |
| ER(-) PR(-) Her2(+) | 12 | 9 (75.0%) | 3 (25.0%) | 10 (83.3%) | 2 (16.7%) | ||||
ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2.
*
P<0.05.