Table 1.
The clinicopathologic characteristics in laryngeal SCC patients (N=46)
| characteristics | |
|---|---|
| Age (y) | 59.2 ± 7.84 |
| Gender (male/female) | 42/4 |
| Differentiation (poor/well) | 25/21 |
| Localization(glottic/supraglottic/subglottic) | 33/11/2 |
| Lymph node metastasis (negative/positive) | 32/14 |
| TNM stage (I-II/III-IV) | 31/15 |
| Smoking (negative/positive) | 12/31 |
| Alcohol (negative/positive) | 22/19 |
Note: We examined miRNAs by quantitative reverse transcription polymerase chain reaction (qRT-PCR) in 46 consecutive laryngeal specimens from patients with laryngeal SCC (as described below) and compared the results according to the clinicopathological characteristics of the patients. The cohort was composed of 42 males and four females, with a median age of 59.2 years (range, 54-78 years). Among them, no patients were received chemoradiotherapy. The distribution of tumor grades was as follows: Thirty-three patients had glottic tumors, while 11 had supraglottic and 2 hadsubglottic tumors. The pathological tumor TNM stages were I-II in 31 patients and III-IV in 15 patients. There was nodal involvement in 14 patients. The median follow-up period was 38.6 months.