Figure 2.

Six1 promotes glioblastoma cell growth and invasion. (A and B) The effect of Six1 overexpression on glioblastoma cell proliferation was measured by MTT assay (A) and colony formation assay (B). (C) MTT assay was performed to determine the effect of Six1 knockdown on cell growth rate in U-118 cells. (D) Cell invasion was determined by matrigel-coated transwell assay. Cells crossed the Matrigel-coated filter were fixed, stained and counted. *P < 0.05. Data represent the mean ± SEM of three independent experiments.