Fig. 2.
Effect of hypoxic agents on BeWo markers of hypoxia. A: serum-starved BeWo cells were incubated in 0.2 mM DFO or 0.2 mM cobalt chloride for up to 24 h (n = 4). At the time points noted, samples were extracted and analyzed for transferrin receptor (TfR) expression compared with untreated control samples. B: serum-starved BeWo cells were incubated in 0.2 mM DFO or 0.2 mM cobalt chloride for 24 h. Samples were extracted, analyzed for GLUT1 (n = 6), TfR (n = 4), and β-actin (n = 3) expression by slot immunoblotting, and compared with untreated controls. *P < 0.05 vs. control.