Table 2.
Grade 1 N (%) |
Grade 2 N (%) |
Grade 3 N (%) |
Grade 4 N (%) |
|
---|---|---|---|---|
Thrombocytopenia | 7 (28) | 1 (4) | 1 (4) | 3 (12) |
Constipation | 5 (20) | 3 (12) | 1 (4) | 0 (0) |
Anemia | 6 (24) | 1 (4) | 1 (4) | 0 (0) |
Nausea | 6 (24) | 2 (8) | 0 (0) | 0 (0) |
Transaminitis | 6 (24) | 1 (4) | 0 (0) | 0 (0) |
Vomiting | 3 (12) | 2 (8) | 0 (0) | 0 (0) |
Fatigue | 5 (20) | 0 (0) | 0 (0) | 0 (0) |
Anorexia | 3 (12) | 0 (0) | 0 (0) | 0 (0) |
Neutropenia | 0 (0) | 0 (0) | 1 (4) | 1 (4) |
Pruritus | 0 (0) | 1 (4) | 0 (0) | 0 (0) |
Sensory neuropathy | 0 (0) | 1 (4) | 0 (0) | 0 (0) |
Rash | 1 (4) | 0 (0) | 0 (0) | 0 (0) |
Mucositis | 1 (4) | 0 (0) | 0 (0) | 0 (0) |
Some patients experienced multiple toxicities. Highest grade of a toxicity experienced by a patient during the study is reported. All grade 3 and 4 toxicities were experienced by 5 patients.