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. Author manuscript; available in PMC: 2015 Jul 9.
Published in final edited form as: J Mol Genet Med. 2014 Sep 30;8(3):129. doi: 10.4172/1747-0862.1000129

Figure 5.

Figure 5

Elastin insufficiency causes metabolic complications in the ApoE-deficient mice. A: Body weight of 16-week-old mice (mean ± SEM; n = 5–18). B: Fed morning glucose measurements of mice on control chow (mean ± SEM; n = 7–19). C: ITT results following a 6-h fast and .75 units/kg insulin injection in Eln WT and Eln+/− mice on an ApoE WT or ApoE−/− background fed control chow (mean ± SEM; n = 6–19). Significance indicated for two-way ANOVA analysis comparing Eln+/−;ApoE−/− mice to all other groups. D: ITT results following a 6-h fast and 0.75 units/kg insulin injection in Eln WT and Eln+/− mice on an ApoE WT or ApoE−/− background fed Western diet for 12 weeks compared with control mice (mean ± SEM; n = 6–19) Significance indicated for two-way ANOVA analysis of Eln+/−;ApoE−/− mice compared to Eln WT;ApoE WT mice.*P≤ 0.05. ✞P=0.08.