Table 1.
Composition of Collagen Preparations Glycated Either Chemically (CML, CEL) or Using Incubation Conditions That Selectively Enrich a Particular AGE (MG-H1, or Pentosidine/CML via Glycoxidation)
| Collagen preparation | CML (nmol/mg collagen) | CEL (pmol/mg collagen) | MG-H1 (pmol/mg collagen) | Pentosidine (pmol/mg collagen) |
|---|---|---|---|---|
| Control | 0.67±0.1 | 83.4±12.2 | 479.4±114.5 | 1.36±0.72 |
| CML-rich collagen | 214.8±39.2 | 32.2±2.1 | 427.1±56.3 | 1.37±0.40 |
| CEL-rich collagen | 1.3±0.2 | 14,946±240 | 357.6±131.4 | 0.77±0.40 |
| Glycoxidized collagen | 9.3±1.2 | 73.8±8.7 | 503.4±150.2 | 674.5±219.5 |
| MG-H1-rich collagen | 1.5±0.3 | 73.7±21.0 | 6,996±1,314 | 0.24±0.51 |
Bold values were used to indicate the most important AGEs for each collagen preparation.
CML, Nɛ-(carboxymethyl)-lysine; CEL, Nɛ-(carboxyethyl)-lysine; MG-H1, methylglyoxal hydroimidazolone.