Skip to main content
. 2015 May 11;125(6):2375–2384. doi: 10.1172/JCI79504

Figure 5. KANK2 colocalizes with and interacts with ARHGDIA in rat glomeruli.

Figure 5

(A) Coimmunofluorescence of KANK2 with PLCE1, ARHGDIA, and RHOA. KANK2 partially colocalizes with PLCE1 and ARHGDIA, which are associated with NS. Anti-PLCE1 and anti-ARHGDIA antibodies were directly fluorescently labeled with Alexa Fluor 547. KANK2 also partially colocalizes with RHOA in rat glomeruli. Scale bar: 25 μm. (B) Coimmunoprecipitation of KANK2 in rat renal glomerular lysates. The protein complex precipitated by an anti-ARHGDIA antibody includes KANK2 as well as RHOA.