Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Saturation curves for [3H]5-HT uptake at SERT in NAc, Str, mPFC, and OFC synaptosomal preparations from a representative individual rat. Nonspecific [3H]5-HT uptake was determined in the presence of 10 μM fluoxetine. Specific uptake (closed circles) was obtained by subtracting nonspecific uptake (open squares) from total uptake (open cirlces). Vmax represents the maximal velocity of [3H]5-HT uptake, and Km represents affinity of 5-HT for SERT.
