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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Mol Cancer Ther. 2015 May 4;14(7):1540–1547. doi: 10.1158/1535-7163.MCT-14-0614

Figure 1. PP2A activity increases after radiation and is inhibited by LB100 in vivo and in vitro.

Figure 1

(A) PP2A activity is expressed as a percentage of control activity based on a phosphatase assay. In vitro PP2A activity in U251 cells is shown, measured at 3 hours and 6 hours after LB100 treatment, radiation (5 Gy), or combined LB100 and radiation treatment. (B) In vivo PP2A activity is shown in U251 xenografts, measured at three hours after treatment with LB100 (2.5 mg/kg), radiation (4 Gy), or combined treatment.