Table 4.
Nutritional Status and Sex Dependent Age-Related Monthly Increase in Absolute CD4 count in Tuberculosis and HIV Co-infected Patients on Concurrent Antiretroviral during Six Months of Tuberculosis treatments in Kampala, Uganda.
| Baseline Nutritional Status | Sex | |||
|---|---|---|---|---|
|
| ||||
| BMI < 18.5 kg/m2 (n=36) | BMI >=18.5 kg/m2 (n =67) | Female (n = 50) | Males (n = 53) | |
| Risk Difference (95% CI) | Risk Difference (95% CI) | Risk Difference (95% CI) | Risk Difference (95% CI) | |
| Age Categories (Years) | Age*time: p = 0.954 | Age*time: p <0.001 | Age*time: p = 0.006 | Age*time: p = 0.795 |
| <25 | −1.5 (−30.9, 28.0) | 56.0 (22.8, 83.4) | 52.8 (18.7, 86.9) | 14.6 (−15.6, 44.7) |
| 25 – 29 | 17.3(−16.6, 49.2) | 50.2 (21.0, 73.2) | 53.7 (25.8, 81.4) | 5.2 (−19.6, 30.0) |
| 30 – 34 | 0.1(−41.1, 41.2) | 36.7 (8.2, 57.2) | 47.0 (11.6, 82.4) | 6.5 (−19.0, 32.1) |
| 35 – 39 | 14.6 (−21.6, 50.8) | 30.1 (−0.3, 60.4) | 26.5 (−21.7, 74.8) | −0.2 (−32.3, 31.9) |
| 40+ | Ref | Ref | Ref | Ref |
| P-value: age*time*BMI: =0.036 | P-value: age*time*sex = <0.001 | |||
Estimates are derived from linear mixed models implemented via SAS PROC Mixed. Model assumed an unstructured covariance for within subject repeated measures of CD4 values. All estimates are adjusted for time, patient sex and lag viral load.