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. Author manuscript; available in PMC: 2016 Sep 15.
Published in final edited form as: Behav Brain Res. 2015 May 28;291:351–360. doi: 10.1016/j.bbr.2015.05.046

Figure 2. General features of infection.

Figure 2

A. Parasite clusters (PCs) were most commonly observed in the ventral white matter of the spinal cord. In this image, a PC in white matter (arrow) impinges of the gray matter (star). Photomicrograph. H&E. 400× magnification. B. A common feature of infection was myelitis, or inflammation of the spinal cord neuropil. Myelitis in these fish was generally multifocal and composed of inflammatory cells that are most likely a combination of granulocytes and microglial cells (arrow). Photomicrograph. H&E. 400× magnification. C. Meninxitis is inflammation of the perineural membranes of the teleost central nervous system, so called because they do not have a true set of meninges as in mammals. Here, granulocytes (white arrow) surround a ruptured PC (black arrow) at the base of a nerve root. D. Encephalitis, inflammation of the brain, was associated with PCs (black arrows) in the medial longitudinal fasciculus, a descending white matter tract in the rhombencephalon. Photomicrograph. H&E. 200× magnification.