Table 1.

Serum ivermectin levels in two patients with Strongyloides hyperinfection following ivermectin administration via PO, NG, PR, and SC routes

Case 1				Case 2
Days after hospital admission*	Anthelminthic agent administered	S. stercoralis filariform larvae result	Serum ivermectin levels (ng/mL)	Days after hospital admission	Anthelminthic agent administered	S. stercoralis filariform larvae result	Serum ivermectin levels (ng/mL)
1	PO albendazole	Present on biopsy from upper GI endoscopy	–	42	NG albendazole	Present in sputum	–
	PR ivermectin				PR ivermectin
2	NG albendazole	Present in vomitus and stool	< 0.19*	43	NG albendazole	Test not performed	< 0.19
	PR ivermectin				NG ivermectin
3	PO ivermectin	Test not performed	0.56†	44	NG albendazole	Test not performed	< 0.19
					NG ivermectin
					SC ivermectin
4	PO ivermectin	Present in stool	–	45	NG albendazole	Test not performed	14.1
					SC ivermectin
5	PO ivermectin	Present in stool	–	46	NG albendazole	Test not performed	13.2
					SC ivermectin
6	PO ivermectin	Present in stool	–	47	SC ivermectin	Present in sputum and stool	23.8
7	PO ivermectin	Present in stool	–	48	SC ivermectin	Present in sputum and stool	42.3
8	PO ivermectin	Test not performed	25.3	49	SC ivermectin	Test not performed	54.9
9	PO ivermectin	Present in stool	–	50	SC ivermectin	Test not performed	–
10	PO ivermectin	Test not performed	–	51	SC ivermectin	Test not performed	–
11	PO ivermectin	Absent from stool	–	–	–	–	–
15	PO ivermectin	Absent from stool	–	–	–	–	–
16	PO ivermectin	Absent from stool	–	–	–	–	–
17	PO ivermectin	Absent from stool	–	–	–	–	–
51	Nil	Absent from stool	–	–	–	–	–

NG = nasogastric; PO = oral; PR = rectal; SC = subcutaneous.

^*Quantifiable limit = 0.19 ng/mL.

^†Sample drawn prior to administration of oral ivermectin.