Fig. 9.

Schematic representation of histopathology matching challenges. Each blue block (numbered 1 to 8) represents a slice of prostate. The bold red lines on each left side of a blue block represent the pathology slide (part of the prostate that is actually visualized under the microscope). The striped bar in the middle represents an OCT scan, and each stripe represents a B-scan. The letters on the left side represent the possible scenarios. A, slice of prostate that looks benign but actually is half tumor (false negative); B, prostate slice that looks malignant and is malignant (true positive); C, prostate slice that looks malignant but is half benign (false positive); and D, prostate slice that looks negative and is negative (true negative). It is clear that because of the matching issues, the difference between benign and malignant attenuation coefficients becomes smaller.