Table 5.

Studies reporting the impact of close or positive resection margins on chest wall recurrence after mastectomy for DCIS

	All Patients in Study			Close or Positive Margins
Study (Author, Year)	Median follow-up	N	CWR rate	Margin definition	N	CWR rate	p value
Current	10.1 y	1546	2.3%	Positive	305	3.0%	0.24
				≤2 mm	220	1.4%	0.84
Childs, 2013 [14]	7.6 y	142	1.4%	positive	21	4.8%
				≤2 mm	23	4.3%
Owen, 2013 [6]	12 y	637	1.9%	Positive	31	6.2%	NS
				<2 mm	35	3.6%	NS
Fitzsullivan, 2013 [8]	6.3 y	803	1%	<1 mm	59	5.0%	<0.001
Chadha, 2012 [7]	4.6 y	211	0.9%	<1 mm	24	8.3%	0.013
Chan, 2011 [13]	8 y	193	NR	Positive	4	0
Godat, 2009 [11]	4.5 y	83	1.1%	<2 mm	20	0
Rashtian, 2008 [12]	61 m	80	7.5%	<2 mm	31	16.1%	0.036
Carlson, 2007 [5]	82.3 m	223	5.1%	<1 mm	19	10.5%	0.32
Spiegel, 2003 [17]	10.5 y	44	0	<1 mm	6	0	NS

CWR chest wall recurrence, m months, N number of patients, NR not reported, NS not statistically significant, y years