TABLE 3.

Proteins identified in the gel bands submitted to trypsin digestion and MS/MS analysis

Identified proteins are listed for each band according to their score calculated by ProteinLynx Global Server software (PLGS). For each protein, its molecular weight (M_r) and the sequence coverage are also indicated. Occasional peptide hits corresponding to keratins have not been included.

Gel band	Protein name	UniProt accession number	PLGS scorea	Mr	Coverage
					%
A	Glycine-tRNA ligase	G3V7G8	5061	81,740	50
	Serum albumin	P02770	2293	68,686	33
	Anionic trypsin 1	P00762	1070	25,942	8
	Calpain 1 catalytic subunit	P97571	532	82,067	32
B	Smyd1	D4A7U4, D4A3D2b	2786	54,948	55
	Myosin light chain kinase 2	G3V731	1507	65,907	29
	F 5-hydroxytryptamine receptor 2B	F1LWG8	1497	95,672	29
	Anionic trypsin 1	P00762	1074	25,942	8
	Aspartyl aminopeptidase	Q4V8H5	896	52,522	46
C	UPF0586 protein C9orf41 homolog	Q5BJZ6	7356	46,355	58.5
	Anionic trypsin 1	P00762	575	25,942	8

^a PLGS score is calculated by the Protein Lynx Global Server (version 2.4) software using a Monte Carlo algorithm to analyze all acquired mass spectral data and is a statistical measure of accuracy of assignation. A higher score implies a greater confidence of protein identity.

^b Current primary accession number.