Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 May 28;290(28):17401–17414. doi: 10.1074/jbc.M114.629808

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 5. — Cell proliferation properties are different between rat and mouse fibroblast-derived iNPCs. Rat and mouse fibroblasts were transduced with BAMX. iNPCs were isolated when neural precursor-like cell morphology was observed. Rat and mouse fibroblasts were induced to iNPCs in N2 medium containing bFGF, FGF8, LIF, and doxycycline (Dx) or bFGF, EGF, FGF8, LIF, and doxycycline, respectively. Cell cycle properties were analyzed by FACS. Interestingly, rat-derived iNPCs (RiNPCs, red) had higher proliferative properties compared with mouse-derived iNPCs (MiNPCs, blue), as evidenced by relative S phase cell abundance. The S phase percentages are 19.63 ± 3.20% versus 4.53 ± 2.30% for rat and mouse iNPCs, respectively (*, p < 0.05).