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. 2015 Jul 10;9:237. doi: 10.3389/fnins.2015.00237

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Copyright © 2015 Detorakis, Chaillet, Palfi and Senova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sustained oscillations amplitude vs. photosensitization degeneracy. We measure the efficiency of the proposed closed-loop stimulation through the amplitude of the remaining oscillations. We consider an increasing degeneracy of α(r), corresponding to an increasing number of STN neurons that do not respond to photostimulation. The three curves correspond to different values of the feedback gain k_c (2, 6, and 12). The darkest curve corresponds to the highest value and the lighter one to the lowest value. The red dashed line indicates the oscillations maximum amplitude when no stimulation is applied.