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. 2015 Jul 10;9:237. doi: 10.3389/fnins.2015.00237

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Copyright © 2015 Detorakis, Chaillet, Palfi and Senova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single light source. The same stimulation signal (Equation 5) is provided to all STN neurons (modulo the function α(r)), with feedback gain k_c = 6.5 and target reference z_ref(r) = 0. Stimulation is ON at time t = 0.5 s. Left: time evolution of the mean activities of GPe (red) and STN (black). Right: time evolution of the closed-loop stimulation signal (Equation 5) (no longer position-dependent). This figure validates the possibility to apply proportional closed-loop stimulation by using a single light source.