Table 1.

Qualitative changes in arterial gene expression in response to altered Notch and/or Alk1 signalling^a

	Dorsal aorta			Cranial arteries
	Wild-type	alk1 mutant/morphant		Wild-type	alk1 mutant/morphant
	LY411575	DMSO	LY411575	LY411575	DMSO	LY411575
tp1:egfp	↓↓↓	NC	↓↓↓	↓↓↓	NC	↓↓↓
hey2	NC	NC	↓	↓↓	NC	NC
efnb2a	↓↓	NC	↓↓↓	NC	NC	NC
dll4	↓↓↓	↑	↓↓↓	↓↓↓	↑	↓↓↓

^aEmbryos were treated with 1% DMSO or 10 µmol/L LY411575, 23–36 hpf, and analysed by in situ hybridization at 36 hpf. Table indicates increased (up arrows), decreased (down arrows; number of arrows indicates qualitative strength of response), or no change (NC) in expression compared with DMSO-treated wild-type embryos.