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. Author manuscript; available in PMC: 2015 Jul 10.
Published in final edited form as: Bioorg Med Chem Lett. 2012 Mar 8;22(9):3317–3322. doi: 10.1016/j.bmcl.2012.03.006

Figure 1.

Figure 1

(A) Demonstration that high fluoride concentration in S. cerevisiae culture causes loss of cell viability. Cells were cultured in liquid medium in the presence of 300 mM fluoride for the times (in minutes) indicated and then plated on solid medium in the absence of added fluoride. Plate images were recorded after extended incubation and colonies were counted. See Supplementary data for all methods details. (B) Plots of the numbers of colonies present versus incubation time as noted in A.