Table IV. Use of clomiphene citrate compared to letrozole in 17 patients having both therapies (38 cycles).
Letrozole | Clomiphene citrate | p value1 | |
---|---|---|---|
Age during cycle | 36.6 (4.5) | 37.1 (4.3) | 0.593 |
Peak estradiol (ng/ml) | 360 (212) | 916 (673) | 0.002 |
Number of follicles > 16 mm | 1.9 (0.8) | 1.5 (1.2) | 0.134 |
Number of mature oocytes | 2.4 (1.4) | 3.1 (1.9) | 0.194 |
Number of fertilized oocytes | 1.7 (1.2) | 2.5 (1.8) | 0.127 |
Number of high quality embryos | 1.0 (1.0) | 1.2 (0.9) | 0.617 |
Number of embryos transferred | 1.4 (0.7) | 1.9 (0.9) | 0.333 |
Cases with a single embryo transferred | 10 (58.8%) | 8 (47.1%) | 0.732 |
Endometrial thickness at hCG (mm) | 7.1 (2.2) | 7.6 (2.2) | 0.501 |
Endometrial thickness at transfer (mm) | 10.2 (1.8) | 9.9 (2.2) | 0.635 |
Clinical pregnancies | 3 (15.8%) | 3 (15.8%) | 1.0 |
Live births | 2 (13.3%) | 3 (15.8%) | 1.0 |
1Two sided paired t test (pairing of cycles completed in time period closest to each other) and Fisher’s exact test