. 2015 Jul 10;5:12069. doi: 10.1038/srep12069

Table 1. Characteristics of studies included in the current meta-analysis.

Surname	Year	Country	Ethnicity	Source	Genotype method	Case				control				MAF	HWE	Score
Surname	Year	Country	Ethnicity	Source	Genotype method	WW	VW	VV	ALL	WW	VW	VV	ALL	MAF	HWE	Score
For rs1447295 C>A (region1)
Chan	2013	Singapore	Asian	HB	Illumina 1M chip	180	92	17	289	94	44	5	143	0.19	0.957	7
Schumacher	2007	USA	Caucasians	PB	TaqMan	8462	2736	268	11466	10344	2472	172	12988	0.11	0.079	14
Zheng	2007	USA	Caucasians	HB	iPLEX	1169	346	31	1546	485	82	4	571	0.08	0.794	11
Joung	2012	Korea	Asian	HB	iPLEX	114	67	12	193	127	38	3	168	0.13	0.936	7
Francisco	2013	Chile	Caucasians	HB	TaqMan	56	23	4	83	16	4	1	21	0.14	0.309	4
Terada	2008	Japan	Asian	HB	PCR-RFLP	310	172	25	507	335	165	11	511	0.18	0.071	9
Okobia	2011	USA	Africa-American	HB	TaqMan	156	162	36	354	173	207	58	438	0.37	0.291	11
Brankovie	2013	Sebia	Caucasians	HB	PCR-RFLP	86	61	3	150	11	82	7	100	0.48	0.000	7
Suurinirmi	2007	USA	Caucasians	PB	TaqMan	435	136	11	582	427	107	4	538	0.11	0.390	15
Zeegers	2011	USA	Caucasians	PB	TaqMan	224	53	4	281	196	64	7	267	0.15	0.523	10
Salinas	2008	USA	Caucasians	PB	TaqMan	937	288	27	1252	994	225	14	1233	0.10	0.753	15
Benford	2010	USA	Africa-American	HB	TaqMan	86	77	26	189	237	221	65	523	0.34	0.000	8
Liu	2012	China	Asian	PB	PCR-RFLP	150	102	8	260	197	86	4	287	0.16	0.111	11
Liu	2009	Japan	Asian	HB	TaqMan	217	149	25	391	218	89	16	323	0.19	0.088	8
Severi	2007	Australian	Caucasians	PB	TaqMan	595	212	14	821	586	135	11	732	0.11	0.319	13
Wokolorczyk	2010	Poland	Caucasians	HB	PCR-RFLP	515	156	19	690	484	115	3	602	0.10	0.165	8
Chen	2009	Taiwan	Asian	PB	TaqMan	215	119	6	340	253	75	9	337	0.14	0.237	10
Cheng	2008	USA	Caucasians	HB	TaqMan	318	97	2	417	344	69	4	417	0.09	0.795	11
Cheng	2008	USA	Africa-American	HB	TaqMan	39	44	6	89	43	35	11	89	0.32	0.919	11
Zheng	2010	China	Asian	PB	iPLEX	173	96	15	284	110	35	6	151	0.16	0.147	12
For rs16901979 C>A (region2)
Chan	2013	Singapore	Asian	HB	Illumina 1M chip	139	119	31	289	64	68	12	144	0.32	0.302	7
Joung	2012	Korea	Asian	HB	iPLEX	99	81	14	194	100	57	12	169	0.24	0.333	7
Okobia	2011	USA	Africa-American	HB	TaqMan	81	158	99	338	131	193	102	426	0.47	0.064	11
Chen	2010	Taiwan	Asian	HB	TaqMan	148	148	35	331	173	138	24	335	0.28	0.62	11
Benford	2010	USA	Africa-American	HB	TaqMan	45	97	50	192	188	237	87	512	0.40	0.406	8
Cheng	2008	USA	Caucasians	HB	TaqMan	375	41	1	417	393	22	1	416	0.03	0.252	11
Cheng	2008	USA	Africa-American	HB	TaqMan	23	43	23	89	27	50	11	88	0.41	0.1	11
For rs6983267 T>G (region3)
Chan	2013	Singapore	Asian	HB	Illumina 1M chip	89	136	63	288	47	74	23	144	0.42	0.493	7
Zheng	2007	USA	Caucasians	HB	iPLEX	495	771	285	1551	142	299	132	573	0.49	0.293	11
Joung	2012	Korea	Asian	HB	iPLEX	56	92	46	194	51	86	31	168	0.44	0.618	7
Francisco	2013	Chile	Caucasians	HB	TaqMan	19	33	30	82	5	13	3	21	0.45	0.253	4
Terada	2008	Japan	Asian	HB	PCR-RFLP	211	219	77	507	206	225	80	511	0.38	0.94	9
Okobia	2011	USA	Africa-American	HB	TaqMan	307	34	2	343	373	52	1	426	0.06	0.562	11
Brankovie	2013	Sebia	Caucasians	HB	PCR-RFLP	53	80	17	150	69	129	52	250	0.47	0.561	7
Salinas	2008	USA	Caucasians	PB	PCR-RFLP	364	652	242	1258	313	617	308	1238	0.50	0.91	15
Liu	2012	China	Asian	PB	PCR-RFLP	70	137	53	260	94	137	51	282	0.42	0.93	11
Liu	2009	Japan	Asian	HB	TaqMan	151	181	59	391	147	151	25	323	0.31	0.104	8
Papanikolopoulou	2011	Greece	Caucasians	HB	TaqMan	16	46	24	86	39	47	13	99	0.37	0.844	6
Cheng	2008	USA	Caucasians	HB	TaqMan	76	215	126	417	106	206	105	417	0.50	0.807	11
Cheng	2008	USA	Africa-American	HB	TaqMan	74	14	1	89	74	11	4	89	0.11	0.001	11
Zheng	2010	China	Asian	PB	iPLEX	86	134	62	282	51	72	29	152	0.43	0.69	12
Penney	2009	USA	Caucasians	PB	iPLEX	400	644	261	1305	372	707	323	1402	0.48	0.714	15
Penney	2009	USA	Caucasians	PB	iPLEX	1184	1776	812	3772	69	134	46	249	0.45	0.177	15

HB, Hospital based; PB, Population based; PCR-RFLP, Polymorphism chain reaction-restriction fragment length polymorphism; MAF, Minor allele frequency; HWE, Hardy-Weinberg equilibrium. WW, wild homozygous; WV, heterozygous; VV, variant homozygous.