Table 2. Univariate Linear Regression Model Parameter Estimates.
| Variable | Estimate (β) | StdErr | tValue | P-value |
|---|---|---|---|---|
| Age | −0.27775 | 0.07460 | −3.72 | 0.0002 |
| BMI | −0.95687 | 0.27199 | −3.52 | 0.0005 |
| HOMA IR | −4.85829 | 0.88828 | −5.47 | <0001 |
| IRI | −1.46830 | 0.25754 | −5.70 | <0001 |
| Glucose | −0.09380 | 0.04657 | −2.01 | 0.0442 |
| SBP | −0.17848 | 0.04333 | −4.12 | <0001 |
| DBP | −0.30613 | 0.08728 | −3.51 | 0.0005 |
| RBC | 0.07289 | 0.02294 | 3.18 | 0.0015 |
| Hb | 1.91436 | 0.72883 | 2.63 | 0.0087 |
| Hct | 0.95129 | 0.26084 | 3.65 | 0.0003 |
Dependent Variable: SNCA concentration (ng/dL).
Univariate linnear regression model for each study variable. HOMA- IR displayed high β values (−4.85, p < 0.0001) together with IRI (−1.46, p < 0.0001). Hb and Hct were also correlated with SNCA serum levels in a lower degree. SNCA, alpha synuclein; Age (years); BMI, Body Mass Index (kg/cm2); HOMA IR, Homeostatic model assessment for insulin resistance (HOMAIR Units); IRI, Immunoreactive insulin (μU/mL); Glucose, fasting blood glucose (mg/dL); SBP, systolic blood pressure (mmHg); DBP, diastolic blood pressure (mmHg); RBC, red blood cells count (X10,000 cells/μL); Hb, hemoglobin (g/dL); Hct, hematocrit, Hct (%). n = 1152.