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. Author manuscript; available in PMC: 2015 Jul 10.
Published in final edited form as: Cell. 2015 Feb 5;160(4):745–758. doi: 10.1016/j.cell.2015.01.012

Figure 6. Mice Lacking JNK in Macrophages Are Protected from Diet-Induced Hepatic Insulin Resistance.

Figure 6

(A and B) Plasma and WAT macrophage IL-6 concentrations.

(C) Glucose infusion rate to maintain euglycemia during a hyperinsulinemic-euglycemic clamp.

(D) Liver acetyl CoA concentrations.

(E) Hepatic glucose production.

(F) Liver PC activity.

(G and H) Whole-body palmitate and glycerol turnover.

**p < 0.01, ***p < 0.001, ****p < 0.0001 versus basal mice; §p < 0.05, §§§p < 0.001, §§§§p < 0.0001 versus wild-type, clamped mice. Data are mean ± SEM of n = 10 (WT), 8 (m§JNK KO), or 10 (m§JNK KO+IL-6) per group. The groups were compared by ANOVA with Bonferroni’s multiple comparisons test. See also Figure S7.