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. 2015 Feb 3;70(6):1751–1756. doi: 10.1093/jac/dkv006

Table 3.

Mean log10 cfu/mL reductions for C. difficile 630 and 5325 following 24 h of exposure to SMT19969, vancomycin or fidaxomicin

Strain Agent Mean log10 reductions in cfu/mL
1 × MIC 2 × MIC 5 × MIC 10 × MIC 20 × MIC
630 SMT19969 3.61 2.17 >3.82a >3.82a >3.82a
vancomycin 3.25 3.22 2.99 3.46 3.59
fidaxomicin 2.45 >2.87a >2.87a >2.87a >2.87a
5325 SMT19969 2.60 1.62 2.73 3.16 3.33
vancomycin 1.14 2.65 1.82 1.81 1.46
fidaxomicin 2.41 2.16 >2.64a >2.64a >2.64a

aReduced to below LOD.