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. 2015 Jun;10(6):958–964. doi: 10.4103/1673-5374.158361

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of hydrogen-rich saline on caspase-3 immunoreactivity in rats with spinal cord injury (immunohistochemical staining, × 200).

(A) SP group (sham-operated plus physiological saline); (B) SH group (spinal cord injury plus hydrogen-rich saline); (C) SSP group (spinal cord injury plus physiological saline). Nuclei of caspase-3-immunoreactive apoptotic cells (arrows) were stained brown, and positive cells could be seen at each stage in the SH and SSP groups. At 24 and 48 hours and 1 and 2 weeks after the injury, caspase-3 expression was greater in the SSP group than in the SH group.