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. Author manuscript; available in PMC: 2015 Jul 10.
Published in final edited form as: Sci Transl Med. 2015 Jan 21;7(271):271ra8. doi: 10.1126/scitranslmed.3010257

Figure 3. Cntnap2 mutant mice show reduced central OXT levels at P30.

Figure 3

(A) Representative images of OXT immunoreactivity in different anterio-posterior levels of the PVN in Cntnap2 KO and WT controls at P30. Scale bar: 100 µm. (B) Stereological counts of OXT positive cells in the PVN region of both genotypes at P30 (n=4 mice, 2M-2F, per genotype). Student t-test, p=0.03. (C) Quantification of OXT levels in whole brain extracts by radioimmunoassay at P30 (n=10 mice, 5M-5F, per genotype). Student t-test, p=0.01. M=male, F=female. Box-plots represent the median plus the 25th and 75th percentiles. Whiskers represent the minimum and maximum values. The mean is represented as a plus (+) sign.