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. 2015 May 6;113(12):1985–1992. doi: 10.1017/S0007114515001166

Table 2.

Associations of customised birth weight centile with indicators of iron status during pregnancy in the Baby's Vascular health and Iron in Pregnancy study (Differences and 95 % confidence intervals)

Difference in birth weight centile mean*
Predictor Unadjusted difference 95 % CI for unadjusted difference P Adjusted difference 95 % CI for adjusted difference P n (multivariable model)
Maternal sF at 12 weeks gestation (per 10 μg/l change) − 0·1 − 1·0, 0·6 0·9 0·1 − 0·6, 0·7 0·9 341
Maternal Fe depletion at 12 weeks gestation (sF < 15 μg/l) − 4·2 − 11·3, 2·3 0·3 − 4·6 − 11·7, 2·5 0·2 341
Maternal sTfR at 12 weeks gestation (per nmol/l) − 0·2 − 0·7, 0·4 0·5 − 0·3 − 0·8, 0·3 0·3 341
Maternal log sTfR:sF ratio at 12 weeks gestation (per μg/l) − 0·8 − 3·4, 1·7 0·5 − 1·2 − 3·8, 1·3 0·3 341
Maternal Hb at ≤ 20 weeks gestation (per 10 g/l) 1·4 − 1·7, 4·5 0·4 1·0 − 2·0, 4·1 0·6 326
Maternal Hb at >20 weeks gestation (per 10 g/l) − 0·8 − 3·7, 2·2 0·6 − 1·2 − 4·4, 1·4 0·3 334
Maternal anaemia at ≤ 20 weeks gestation ( < 110 g/l) − 15·0 − 29·2, − 1·0 0·04 − 11·2 − 25·4, 3·1 0·1 326
Maternal anaemia at >20 weeks gestation ( < 105 g/l) − 4·5 − 13·1, 4·2 0·3 − 1·4 − 10·1, 7·3 0·8 334

sF, serum ferritin; sTfR, serum transferrin receptor.

*

Customised birth weight centile (takes into account maternal pre-pregnancy weight, height, ethnicity, parity, gestational age and baby's sex).

Adjusted for maternal age, smoking, gestational diabetes, pre-eclampsia and area deprivation score (Index of Multiple Deprivation).