Table 2.
Associations of customised birth weight centile with indicators of iron status during pregnancy in the Baby's Vascular health and Iron in Pregnancy study (Differences and 95 % confidence intervals)
| Difference in birth weight centile mean* | |||||||
|---|---|---|---|---|---|---|---|
| Predictor | Unadjusted difference | 95 % CI for unadjusted difference | P | Adjusted difference† | 95 % CI for adjusted difference | P | n (multivariable model) |
| Maternal sF at 12 weeks gestation (per 10 μg/l change) | − 0·1 | − 1·0, 0·6 | 0·9 | 0·1 | − 0·6, 0·7 | 0·9 | 341 |
| Maternal Fe depletion at 12 weeks gestation (sF < 15 μg/l) | − 4·2 | − 11·3, 2·3 | 0·3 | − 4·6 | − 11·7, 2·5 | 0·2 | 341 |
| Maternal sTfR at 12 weeks gestation (per nmol/l) | − 0·2 | − 0·7, 0·4 | 0·5 | − 0·3 | − 0·8, 0·3 | 0·3 | 341 |
| Maternal log sTfR:sF ratio at 12 weeks gestation (per μg/l) | − 0·8 | − 3·4, 1·7 | 0·5 | − 1·2 | − 3·8, 1·3 | 0·3 | 341 |
| Maternal Hb at ≤ 20 weeks gestation (per 10 g/l) | 1·4 | − 1·7, 4·5 | 0·4 | 1·0 | − 2·0, 4·1 | 0·6 | 326 |
| Maternal Hb at >20 weeks gestation (per 10 g/l) | − 0·8 | − 3·7, 2·2 | 0·6 | − 1·2 | − 4·4, 1·4 | 0·3 | 334 |
| Maternal anaemia at ≤ 20 weeks gestation ( < 110 g/l) | − 15·0 | − 29·2, − 1·0 | 0·04 | − 11·2 | − 25·4, 3·1 | 0·1 | 326 |
| Maternal anaemia at >20 weeks gestation ( < 105 g/l) | − 4·5 | − 13·1, 4·2 | 0·3 | − 1·4 | − 10·1, 7·3 | 0·8 | 334 |
sF, serum ferritin; sTfR, serum transferrin receptor.
Customised birth weight centile (takes into account maternal pre-pregnancy weight, height, ethnicity, parity, gestational age and baby's sex).
Adjusted for maternal age, smoking, gestational diabetes, pre-eclampsia and area deprivation score (Index of Multiple Deprivation).