(A) Serum levels of miR-223 from atherosclerotic apolipoprotein E knockout mice and from patients with higher atherosclerosis levels compared with normal control subjects. (B) MiR-223 levels rose in balloon-injured rat carotid arteries, (C) ligation-injured mouse carotid arteries, (D) atherosclerotic aortas from apolipoprotein E knockout mice, and (E) atherosclerotic human arteries compared with normal controls. (F) The successful rat carotid artery balloon injury, (G) mouse carotid artery ligation injury in mice, (H) mouse atherosclerotic aorta, and (I) human atherosclerotic artery were confirmed by histology. *p < 0.05 compared with control groups. Abbreviations as in Figure 1.