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. Author manuscript; available in PMC: 2015 Dec 16.
Published in final edited form as: J Am Coll Cardiol. 2015 Jun 16;65(23):2526–2537. doi: 10.1016/j.jacc.2015.03.570

FIGURE 4. Cellular Functions of miR-223 in VSMCs.

FIGURE 4

The effect of miR-223 on PDGF-induced VSMC proliferation as determined by (A) MTT assay and by (B) 5-ethynyl-2′-deoxyuridine (EdU) method. (C) The EdU-positive VSMCs from different groups. The effect of miR-223 on (D) VSMC migration determined by the Boyden chamber assay seen in (E) representative images from different groups. (F) The effect of miR-223 on VSMC apoptosis determined by the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) analysis, seen in (G) representative images from different groups. *p < 0.05 compared with control groups. DAPI = 4′,6-diamidino-2-phenylindole; other abbreviations as in Figure 1.