Chemoprevention regimen			Trials
Drug	Dose	Frequency
Chloroquine	300 mg	Weekly	Cot 1992 BFA; Cot 1995 CMR; Ndyomugyenyi 2000 UGA; Villegas 2007 THA
Pyrimethamine	100 mg	Monthly	Morley 1964 NGA
	25 mg	Weekly	Nahlen 1989 NGA
Proguanil	100 mg	Daily	Fleming 1986 NGA
Pyrimethamine‐dapsone	25 mg/100 mg	Every two weeks	Greenwood 1989 GMB
	12.5 mg/100 mg	Weekly	Menendez 1994 GMB
Sulfadoxine‐pyrimethamine	1500 mg/75 mg	One to two doses	Shulman 1999 KEN
		Two doses	Challis 2004 MOZ; Menendez 2008 MOZ; Njagi 2003i KEN; Parise 1998i KEN
		Up to four doses	Mbaye 2006 GMB
		Monthly	Parise 1998ii KEN
Mefloquine	500 mg loading dose, 250 mg weekly for 4 weeks, 125 mg weekly until delivery	Weekly	Nosten 1994 THA