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. 2015 Jul 11;46(1):80. doi: 10.1186/s13567-015-0212-1

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© Takanashi et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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CyPA is secreted in cattle during inflammation. Immunohistochemical analysis shows that extracellular CyPA is abundantly found in alveoli and ducts of bovine mammary gland with mastitis (shown by arrowheads). A-C and E-G (both of which were stained with anti-CyPA antibody) are images showing individual healthy cattle and individual cattle with mastitis, respectively. D (healthy) and H (mastitis) are images stained with control antibody. Scale bar = 100 μm.