Table 3.
Comparison of carrier frequency of KIR genes in three ethnic minority populations in China
| KIR | Tibetan | Kazakh | Uyghur | P values | ||
|---|---|---|---|---|---|---|
| N = 224 | N = 125 | N = 130 | Tibetan vs Kazakh | Tibetan vs Uyghur | Kazak vs Uyghur | |
| %CF(n) | %CF(n) | %CF(n) | ||||
| A haplotype associated | ||||||
| 2DL1 | 99.1 (222) | 98.4 (123) | 98.5 (128) | |||
| 2DL3 | 98.7 (221) | 95.2 (119) | 92.3 (120) | 0.0056 | ||
| 3DL1 | 97.3 (218) | 95.2 (119) | 91.5 (119) | 0.0028 | ||
| 2DS4-f | 86.6 (194) | 64.8 (81) | 62.3 (81) | <0.0001 | <0.0001 | |
| 2DS4-v | 29.5 (66) | 59.2 (74) | 60.8 (79) | <0.0001 | <0.0001 | |
| B haplotype associated | ||||||
| 2DL2 | 24.6 (35) | 33.6 (42) | 43.8 (57) | 0.0003 | ||
| 2DL5 | 38.4 (86) | 47.2 (59) | 59.2 (77) | 0.0002 | ||
| 2DS1 | 36.2 (81) | 39.2 (49) | 40.8 (53) | |||
| 2DS2 | 25.0 (56) | 36.8 (46) | 46.9 (61) | 0.0277 | <0.0001 | |
| 2DS3 | 12.5 (28) | 23.2 (29) | 33.9 (44) | 0.0146 | <0.0001 | |
| 2DS5 | 31.3 (70) | 33.6 (42) | 33.1 (43) | |||
| 3DS1 | 35.3 (79) | 36.0 (45) | 39.2 (51) | |||
| Framework/pseudogenes | ||||||
| 2DL4 | 100 (224) | 100 (125) | 100 (130) | |||
| 3DL2 | 100 (224) | 100 (125) | 100 (130) | |||
| 3DL3 | 100 (224) | 100 (125) | 100 (130) | |||
| 2DP1 | 99.1 (222) | 98.4 (123) | 100 (130) | |||
| 3DP1 | 100 (224) | 100 (125) | 100 (130) | |||
Frequency (%CF) of carriers of each gene is expressed as a percentage and defined as the number of donors carrying the gene (n) divided by the number of donors studied (N) in the given populations. The p values are given only for those pairwise comparisons indicating significant (P < 0.05) difference.