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. 2015 Jul 10;17(1):176. doi: 10.1186/s13075-015-0691-5

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© Dean et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Representative immunofluorescent images of torn human supraspinatus to show cell types expressing nociceptive neuromodulators. Panel shows dual antibody labelling for CD206 (green) with (a) glutamate (violet), (b) PGP9.5 (violet) and (c) NMDAR1 (red). Cyan represents POPO-1 nuclear counterstain. NMDAR1 co-localised with CD206-positive cells, whereas PGP9.5 and glutamate were predominantly expressed by resident tendon cells. Scale bar: 20 μm. mGluR metabotropic glutamate receptor, NMDAR N-methyl-D-aspartate receptor, PGP9.5 protein gene product 9.5