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. 2015 Jul 10;10(7):e0132757. doi: 10.1371/journal.pone.0132757

Fig 6. Notch induced downregulation of ΔNp63 is not mediated through IRF6.

Fig 6

Relative mRNA expression levels of IRF6 and ΔNp63 (A) and protein expression of IRF6 (B) in MCF10A cells infected with (i) two control viruses (grey bars), (ii) NICD and control shRNA expressing viruses (black bars) or (iii) NICD and IRF6 shRNA (shIRF6) expressing viruses (light grey bars) (Left: representative western image, Right: Quantification of the protein bands). Values represent mean±S.D. of three independent experiments. (In panel B, first lane was loaded on the same gel into a well that is not adjacent to the other two wells.) (p values: *: <0.04, **: <0.007).