Table 2. Alignments of C. thermophilum Mex67Mtr2 and H. sapiens NXF1NXT1.

The structures of the individual domains from C. thermophilum Mex67Mtr2 were compared with the individual domain structures of H. sapiens NXF1NXT1 using the super command in PyMOL using default settings. The global sequence identity between Mex67 and NXF1 was calculated using NEEDLE. The sequence identities for the individual domains were calculated by submitting the two PDB files to the DaliLite pairwise alignment server. The numbers of residues that were used in the alignment to generate the resulting values are given in parentheses.

	Sequence identity (%)	C r.m.s.d. ()
Global sequence alignment	23
RRM domain	15 (73)	1.5 (59)
LRR domain	27 (135)	1.5 (116)
NTF2L domain	22 (153)	1.9 (109)
UBA domain	29 (55)	0.75 (41)
Mtr2NXT1	22 (124)	0.70 (75)