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. 2015 Jul 10;10(7):e0132697. doi: 10.1371/journal.pone.0132697

Fig 1. Kinetics of induction of anemia in cadmium treated mice.

Fig 1

Mice were given cadmium chloride dissolved in drinking water (50 ppm and 1000 ppm). Blood samples from mice in control and cadmium-treated groups were collected at different time points and analyzed on an automated cell counter. Erythrocyte count and hemoglobin content in 50 ppm group over a period of 6 weeks are given in panels A and C respectively (ANOVA test for effect of cadmium on erythrocyte count, p = 0.057; on hemoglobin level p<0.001). Erythrocyte count and hemoglobin content at different time intervals in mice exposed to 1000 ppm of cadmium chloride have been shown in panels B and D respectively (ANOVA test for effect of cadmium on erythrocyte count, p = 0.001; on hemoglobin level p<0.001). Each point on the graph represents mean ± SEM of observations on 10–15 mice. *p<0.05, **p<0.01 and ***p<0.005 for comparison of the groups (Student t-test).