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. 2015 Jul 10;10(7):e0132604. doi: 10.1371/journal.pone.0132604

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© 2015 Manocha et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 1 — Microglial BV2 cells were untreated (control), vehicle DMSO treated, or treated with 0.5nM, 5nM, 50nM, 0.5 μM, 5μM and 50 μM (A) LDDN-0003499, (B) LDDN-0075935, (C) LDDN-0125694, and (D) LDDN-0127164 for 24h. Following compound treatment, media were used to perform LDH release assay to determine cell viability. Three independent experiments with 8 replicates each were performed and absorbance values graphed and averaged ± SD.