Table 2.

Review of reported cases with TAFRO syndrome

Age	N	Symptoms and Laboratory data								Treatment	Clinical course	References
		Thrombo -cytopenia	Anasarca	Myelo -fibrosis	Renal dysfunction	Organo -megaly	IL-6 elevation	VEGF elevation	Histologic type
47–56	5	5+	5+	5+	2+	5+	4+	2+	1 HV	3 CS, 3 CsA, 1 IVIg, 1 CY	4 CR, 1 died of CMV infection	9
43	1	+	+	−	+	+	+	+	HV	CS, Rit, Toc	CR	7
57, 73	2	2+	2+	1+	2+	2+	2+	−	1 MCD-like 1 mixed	1 CS, 1 CHOP+VP-16	2 died of sepsis	28
49	1	+	+	+	−	+	+	+	MCD like	CS, CsA	CR	29
47	1	+	+	+	+	+	+	NA	PC	CS, Toc	CR	8
56	1	+	+	−	+	+	+	+	PC	CS, Toc, Thal	CR	Present case

IL-6, interleukin-6; VEGF, vascular endothelial cell growth factor; MCD, multicentric Castleman's disease; CMV, cytomegalovirus.