Table 1.

Clinical manifestations of AITL (numbers are presented as % except Patient number and Age)

Authors	Federico 1	Tokunaga 2	Mourad 3	Lachenal 9	Siegert 4	Aozasa 25
Patient number	243	207	157	77	62	44
Age, years
Mean	65	67	62	64.5	64	64
Range	20–86	34–91	20–89	30–91	21–87	25–84
Male sex	56	64		56	58	55
Lymphadenopathy
Generalized	76			90		84
Localized	24			9		16
Skin rash	21		44	45	49	27
B symptoms	69	60	72	77	68
Splenomegaly	35			51		39
Hepatomegaly	26			26		52
Effusion/edema/ascites		14	26	25	>38
Bone marrow involvement	28	29	47
Extranodal sites, >1	27	23	46
Anemia	33	61	65	51	57	20
Platelet count <150 × 109/L	25	34		20	20
Elevated LDH	60	75	66	71	70
Elevated C-reactive protein	35	46		67
Hypergammaglobulinemia	30		50	51	51	64
Positive Coombs test	13	46	33	58	32

LDH, Lactate dehydrogenase.