Table 1. The cAMP levels (pmol/ng protein; mean values ± SEM; n = 6/group) in five brain regions after acute antipsychotic treatment.
| PFC | NAc | CPu | VTA | SN | |
|---|---|---|---|---|---|
| Aripiprazole | 75.0±16.6 | 55.0±7.9 | 34.3±7.5 | 166.7±32.7 | 85.0±13.3 |
| Bifeprunox | 49.0±7.4* | 54.2±4.4 | 41.4±8.1 | 106.0±14.4 | 90.3±18.3 |
| Haloperidol | 74.8±15.2 | 58.9±3.2 | 40.7±3.5 | 115.8±8.3 | 132.5±22.5 |
| Control | 105.0±5.7 | 60.4±5.4 | 34.5±5.5 | 123.9±14.8 | 99.2±13.2 |
* p < 0.05
Abbreviations: CPu, caudate putamen; NAc, nucleus accumbens; PFC, prefrontal cortex; SN, substantia nigra; VTA, ventral tegmental area.