Figure 7.
Fas–FasL interaction-dependent apoptosis by acitretin in SCL-1 cells. SCL-1 cells were treated with 1 μg/ml ZB4 for 10 min., then acitretin (10−5 M) was added, following by incubation for an additional 24 hrs. The cells were then analysed for apoptosis by the Cell Death Detection ELISA. Data are shown as median of three independent cultures in one representative experiment. The experiment shown is representative of three independent experiments showing similar results. *P < 0.01 versus untreated cells. **P > 0.01 versus untreated cells. #P < 0.01 versus acitretin- treated cells.