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. 2008 Jul 24;13(9a):2911–2925. doi: 10.1111/j.1582-4934.2008.00434.x

Figure 8.

Figure 8

Effects of ancrod on gliosis and neuronal viability in Aβ1-42-injected hippocampus. (A) Representative microglial (Iba-1 marker, upper panels), astrocyte (GFAP marker, middle panels) and neuronal (NeuN marker, lower panels) staining at 7 days with PBS, Aβ1-42 and Aβ1-42 plus ancrod treatment. Scale bar represents 100 μm. (B) Quantification of ancrod effects on microgliosis (upper bar graph), astrogliosis (middle bar graph) and neuronal viability (lower bar graph). Results (Iba-1 and NeuN) are expressed as the number of cells per high-power (×400) field. Data are means ± S.E.M. from six animals. *Denotes significant difference for P < 0.05. #Denotes P < 0.05 between Aβ1-42 and Aβ1-42 plus ancrod.