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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Hypertension. 2015 Jun 8;66(2):309–316. doi: 10.1161/HYPERTENSIONAHA.115.05333

Figure 4. Microglia are important for sustained hypertension.

Figure 4

(A) Systolic blood pressure was measured in CD11b-DTR mice treated with Ang II (left) by telemetry transducer or L-NAME (right) by tailcuff. After hypertension induction, mice were treated with i.c.v. DT or saline in the indicated periods. Expression of TNFα and IL-1β (B) and GluN2A (C) in the PVN of naïve, Ang II or Ang II + i.c.v. DT treated CD11b-DTR mice were analyzed by ELISA and Western Blot, respectively. (D) The levels of kidney norepinephrine (NE) and plasma vasopressin (AVP) were analyzed by ELISA. *P<0.05 by Two-way ANOAVE in (A) and by one-way ANOVA in (B–D).