Table 2.
Changes in BMI body composition parameters at 6 months and 1 years of aromatase inhibitor therapy according to genotypes of the rs700518 polymorphism
% Changes in BMI and Body Composition at 6 months | % Changes in BMI and Body Composition at one year | |||||
---|---|---|---|---|---|---|
GG (=18) | GA+AA N=(64) | P | GG (N=18) | GA+AA (N=64) | *P | |
BMI | 0.90±5.20 | -0.41±7.78 | 0.44 | 1.62±8.92 | 0.25±8.12 | 0.53 |
Fat mass index | -2.48±6.39 | -0.76±8.02 | 0.45 | 1.57±8.82 | -1.13±8.30 | 0.23 |
Trunk fat mass index | -2.24±9.51 | -2.20±10.43 | 0.99 | 4.63±11.73 | -2.21±11.95 | 0.03 |
Fat-free mass index | 0.19±2.92 | 0.29±4.81 | 0.94 | -2.12±3.40 | 0.39±3.64 | 0.01 |
Values are Means±SD; BMI: body mass index;
T-test for BMI otherwise analysis of covariance adjusted for age