Extended Data Figure 3. Classification of uiDMR histone profiles and uiDMR properties.

a, heatmap of the histone modification profiles for the five types of uiDMRs. The profiles were plotted for each mark across the DMR and the 5kb upstream and downstream and the colors of each cell indicate the input normalized ChIP-seq RPKM. The colors on the left indicate the group of each profile assigned by k-means clustering (red, weak enhancer; orange, promoter-proximal; green, transcribed; blue, unmarked; black poised enhancer). b, A pie chart of the distribution of uiDMRs across the classes defined by k-means clustering.