Fig. 2.

Paraquat elicited a 50% increase in cytosolic $\cdot {\mathrm{O}}_2^{-}$ (DHE fluorescence, n=7, filled bar) as compared to buffer as a negative control (n=7, open bar) and paraquat (n=7, filled bar). The paraquat-induced increase in $\cdot {\mathrm{O}}_2^{-}$ production was abolished by tempol (n=7, p<0.005, gray bar), but was not significantly influenced by catalase (n=7, patterned bar) (*** p<0.005 vs. control, # p<0.005 vs. paraquat).